The true nature of the Jackal's spider-plague has been revealed as the denizens of Manhattan begin mutating into monstrous arachnids! Now under the control of the Spider-Queen, it's up to Spider-Man and the Avengers to stop the wicked web-mistress before she turns the entire human race into her spider-slaves.
Collecting Amazing Spider-Man #670–673 and Venom #7–8.