From across the cosmos, the ancient Builders are cutting a bloody swathe through the galaxy, wiping out planets on their way to annihilate the Earth. With the Avengers off the planet, the mad titan Thanos takes advantage of the situation and launches an attack. But global domination is not his goal; instead he seeks the ancient knowledge of the Inhumans and a deadly secret that has been hidden away for years.
Collecting Infinity #1–3, Avengers (Vol. 5) #18–20, New Avengers (Vol. 3) #9–10.